Text of artical which appeared in the Brittish journal +quot;Nature+quot;, Vol. 323.25, Se

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Text of artical which appeared in the Brittish journal "Nature", Vol. 323.25, September 1986. Mystery Object Amid The Chromosomes ___________________________________ Sir - The very thin object shownbelow like a fragmented crosswordin appearence, was recently foundin one of our routine chromosomepreparations for prenatal diagnosisfollowing aminiocentisis. But whatis it? Is it a man made device? Packingtext as binary coded information onthe miniature scale (the scale baris 10 micro-milimeters) would seemadvantageous. Or is it a naturallyoccuring substance? None of thepossibilities we have been able tothink of would seem to be appro-priate to amniotic fluid, so ifanybody is able to suggest ananswer to this mystery we wouldlike to have it.We are as intrigued as we areignorant. John Wolstenholme Ian Harlow George Clarke Hilary Sheridan Jon Jonasson Mark Crocker Helen MatthewsDepartment of Medical GeneticsChurchill Hospital, Headington,Oxford OX3 7LJ, UK

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