Table 5-1. Beta adrenoceptor blockers used in hypertension. Route of administration is ora

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Table 5-1. Beta adrenoceptor blockers used in hypertension. Route of administration is oral unless otherwise noted. Presc Cat contains the controlled drug and FDA pregnancy safety category codes To calculate dose for over/underweight patients: ______________________________________________________________________ Drug Recommended (available as) Dose Dosing Duration Pres Interval Cat Notes __________________mg____hours_______hours_____________________________ Acebutolol (Sectral: 200, 400 mg caps) 400 12-24 24 Rx;B 1,2 Atenolol (Tenormin: 50, 100 mg tabs) 50-100 24 24 Rx;C 1,2 Labetalol (Normodyne, Trandate: 200,300 mg tabs; 5 mg/mL injection) 200-400 12-24 8-12 Rx;C 3 IV 20 SLOWLY (For hypertensive emergencies) (PgDn key for more drugs) 컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴 Drug Dose Dur Cat Notes 컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴 Metoprolol (Lopressor: 50,100 mg tabs; 1 mg/mL injection) 100-450 q24h 13-19h Rx;B 2 IV 15 SLOWLY in 3 divided doses at 2 min intervals (For early prophylaxis of post-myocardial infarction arrhythmias) Nadolol (Corgard: 40,80,120,160 mg tabs) 40-320 q24h 17-24h Rx;C 1 Pindolol (Visken: 5,10 mg tabs) 5-30 q12h 24h Rx;B 1,4 Propranolol (generic, Inderal: 10,20,40,60,80,90 mg tabs; 1 mg/mL injection; Inderal LA: 80,120,160 mg SR caps) oral 40-320 q12h 8-12h Rx;C 1 IV 1-3 SLOWLY (For arrhythmias) Timolol (Blocadren: 5,10,20 mg tabs) 5-20 q12h 12h Rx;C 1 =========================================================================== NOTES: 1. Dosage should be reduced in patients with impaired renal function. 2. Relatively beta-1 selective. 3. Labetalol has significant alpha-blocking as well as beta-blocking action. 4. Partial agonist; may produce less bradycardia and cardiac depression.

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