Table 3-2. Properties of the Group IB and IC antiarrhythmic drugs. Presc Cat contains the

---
Master Index Current Directory Index Go to SkepticTank Go to Human Rights activist Keith Henson Go to Scientology cult

Skeptic Tank!

Table 3-2. Properties of the Group IB and IC antiarrhythmic drugs. Presc Cat contains the controlled drug and FDA pregnancy safety prescribing category codes Calculate dose for significantly over/underweight patient: Toxicity: _________________________________________________________________________ Drug Recommended Half- Plasma level (Available Dose life Thera- Toxic Presc as) (mg) peutic Route Cat Notes ________________________________________(mg/L)___________________________ GROUP IB: Lidocaine 1-2 1.5-6 >10 Rx;B (generic, Xylocaine: 100 mg/mL IM injection;10,20 mg/mL IV injection; 40,100,200 mg/mL for IV admixtures; premixed IV (5%D/W) also available) 50-100 IV bolus 20-50 mcg/kg.min IV maintenance 4.3 mg/kg IM for emergency use Mexiletine 10-12 0.5-2 >2 Rx;C (Mexitil: 150,200,250 mg caps) 200-400 TID Oral (PgDn key for scroll) 컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴 Drug Dose t Rx-Level-Tx Route Cat Notes 컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴컴 Tocainide 11-15 4-10 >10 Rx;C (Tonocard: 400,600 mg tabs) 400-600 TID Oral ---------------------------------------- GROUP IC: Flecainide 12-27 0.2-1 >1 Rx;C (Tambocor: 100 mg tabs) 100-200 BID Oral Encainide 4-12 Rx;B 1 (Enkaid: 25,35,50 mg caps) 25 Q8-24hr ========================================================================== Footnotes: 1. Half-life of active metabolites of encainide; half-life of encainide is only 1-2 hrs.

---

E-Mail Fredric L. Rice / The Skeptic Tank